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Taking part

This page explains the FREMS-PDPN Study for people who might be interested in joining

General information

We are inviting 356 adults with PDPN to take part in this study.

The FREMS-PDPN Study is looking at whether a nerve stimulation device can reduce pain from the nerve damage caused by diabetes.

You will receive a treatment chosen by chance. The treatments are FREMS (Frequency Rhythmic Electrical Modulated System) or TENS (Transcutaneous Electrical Nerve Stimulation).

Both FREMS and TENS give electrical pulses delivered through stickers on the skin. The nature of these pulses is different between FREMS and TENS, resulting in different biological effects on pain and different responses (short term pain reductions for TENS, usually days, and 3-4 months for FREMS).

FREMS-PDPN Participant Information

If you are considering taking part in the FREMS-PDPN Study, please follow the link below to open the FREMS-PDPN Participant Information Tool. Here you can view the key information needed to decide whether to take part.

MEDICAL TRIAL study logo

Birmingham Clinical Trials Unit
Public Health Building
University of Birmingham
Birmingham B15 2TT

+44 (0)121 415 9128

[email protected]


This study is funded by the National Institute for Health Research (NIHR) Heath Technology Assessment programme (project reference NIHR133599). The views expressed are those of the author(s) and not necessarily those of the NIHR or the Department of Health and Social Care.

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